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Daniel R Southworth

12PUBLICATIONS
67CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsGene and molecular therapyNeurology and neuromuscular diseasesNanotoxicology, health and safetyMedical biochemistry - proteins and peptides (incl. medical proteomics)
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Journal

Publications (12)

Sort by Publication Date:
|Apr 01, 2026
An Optimized Route to the Syringolin Natural Products Enables Combinatorial Synthesis of Selective, Bioactive Inhibitors of the <i><i>Plasmodium falciparum</i></i> 20S Proteasome.

Xilin Gu, Pavla Fajtova, Nicholas L Yan

|Feb 23, 2026
Distinct tau filament folds in familial frontotemporal dementia due to the <i>MAPT</i> S305I mutation.

Henry S Pan, Gregory E Merz, Alissa Nana Li

|Nov 08, 2024
Cryo-EM structure of a novel α-synuclein filament subtype from multiple system atrophy.

Nicholas L Yan, Francisco Candido, Eric Tse

|Sep 12, 2024
Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP.

Cory M Nadel, Saugat Pokhrel, Kristin Wucherer

|Jul 01, 2024
Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly.

Julian R Braxton, Hao Shao, Eric Tse

|Apr 15, 2024
Cryo-EM Structures Reveal Tau Filaments from Down Syndrome Adopt Alzheimer's Disease Fold.

Ujjayini Ghosh, Eric Tse, Hyunjun Yang

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Frequent Collaborators

8 joint publications

Eric Tse

4 joint publications

Gregory E Merz

4 joint publications

Jason E Gestwicki

3 joint publications

Stanley B Prusiner

2 joint publications

Nick A Paras

2 joint publications

Alexandrea N Rizo

2 joint publications

Arthur A Melo

2 joint publications

Julian R Braxton

1 joint publications

Adam L Yokom

1 joint publications

Meredith E Jackrel

Frequent Collaborators

8 joint publications

Eric Tse

4 joint publications

Gregory E Merz

4 joint publications

Jason E Gestwicki

3 joint publications

Stanley B Prusiner

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