Daniel R Southworth

15PUBLICATIONS
74CO-AUTHORS
Life historiesMedical devicesCheminformatics and quantitative structure-activity relationshipsGene and molecular therapyStructure and dynamics of materials
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Publications (15)

|Sep 01, 2026
Cofactor-Free Tau Filaments Are Dynamic and Undergo Structural Evolution Driven by Thermodynamic Control.

|Jul 08, 2026
Hypoxia rescues complex 1-associated disease caused by proteostatic defects.

|Apr 01, 2026
An Optimized Route to the Syringolin Natural Products Enables Combinatorial Synthesis of Selective, Bioactive Inhibitors of the Plasmodium falciparum 20S Proteasome.

Xilin Gu, Pavla Fajtova, Nicholas L Yan

|Feb 23, 2026
Distinct tau filament folds in familial frontotemporal dementia due to the MAPT S305I mutation.

Henry S Pan, Gregory E Merz, Alissa Nana Li

|Jun 04, 2025
Structures of Fab-stabilized CHIP reveal a conformational switch important in E3 ligase and chaperone functions.

|Nov 08, 2024
Cryo-EM structure of a novel α-synuclein filament subtype from multiple system atrophy.

Nicholas L Yan, Francisco Candido, Eric Tse

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Frequent Collaborators

8 joint publications

Eric Tse

5 joint publications

Jason E Gestwicki

4 joint publications

Gregory E Merz

3 joint publications

Stanley B Prusiner