Qingyun J Liu
8PUBLICATIONS
5CO-AUTHORS
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Publications (8)
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|Sep 02, 2025
RSPO2-based peptibodies conjugated with pyrrolobenzodiazepine dimer or camptothecin analogs demonstrate potent anti-tumor activity by targeting the three receptors LGR4/5/6.Yukimatsu Toh, Jianghua Tu, Ling Wu
|Aug 18, 2025
Anti-tumor activity of camptothecin analog conjugate of an RSPO4-based peptibody targeting LGR4/5/6 in preclinical models of colorectal cancer.Yukimatsu Toh, Ling Wu, Jianghua Tu
|Jul 04, 2023
LGR4 and LGR5 form distinct homodimers that only LGR4 complexes with RNF43/ZNRF3 to provide high affinity binding of R-spondin ligands.Yukimatsu Toh, Ling Wu, Soohyun Park
|Aug 18, 2021
Drug Conjugates of Antagonistic R-Spondin 4 Mutant for Simultaneous Targeting of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors 4/5/6 for Cancer Treatment.Jie Cui, Yukimatsu Toh, Soohyun Park
|Dec 02, 2020
Unlike LGR4, LGR5 potentiates Wnt-β-catenin signaling without sequestering E3 ligases.Soohyun Park, Ling Wu, Jianghua Tu
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