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Kenneth Down

3PUBLICATIONS

4CO-AUTHORS

Biologically active moleculesBasic pharmacologyCheminformatics and quantitative structure-activity relationships

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Publications (3)

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|Sep 13, 2021

Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode.

Kenneth Down, Augustin Amour, Niall A Anderson

|Dec 20, 2019

Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a Key Selectivity Target.

Zoë A Henley, Augustin Amour, Nick Barton

|Dec 12, 2018

Discovery of Potent, Efficient, and Selective Inhibitors of Phosphoinositide 3-Kinase δ through a Deconstruction and Regrowth Approach.

Nick Barton, Máire Convery, Anthony W J Cooper

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Frequent Collaborators

1 joint publications

Marcus Bantscheff

1 joint publications

Giovanna Bergamini

1 joint publications

Sophie M Bertrand

1 joint publications

Niall A Anderson

Frequent Collaborators

1 joint publications

Marcus Bantscheff

1 joint publications

Giovanna Bergamini

1 joint publications

Sophie M Bertrand

1 joint publications

Niall A Anderson

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