Kenneth Down

3PUBLICATIONS
4CO-AUTHORS
Biologically active moleculesBasic pharmacologyCheminformatics and quantitative structure-activity relationships
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (3)

|Sep 13, 2021
Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode.

Kenneth Down, Augustin Amour, Niall A Anderson

|Dec 20, 2019
Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a Key Selectivity Target.

Zoë A Henley, Augustin Amour, Nick Barton

|Dec 12, 2018
Discovery of Potent, Efficient, and Selective Inhibitors of Phosphoinositide 3-Kinase δ through a Deconstruction and Regrowth Approach.

Nick Barton, Máire Convery, Anthony W J Cooper

Pageof 1