Adrian Sacher

7PUBLICATIONS
86CO-AUTHORS
Molecular targetsPredictive and prognostic markersCancer therapy (excl. chemotherapy and radiation therapy)
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Publications (7)

|May 13, 2026
mSWI/SNF complex inhibition sensitizes KRAS-mutant lung cancers to targeted therapies via epithelial-mesenchymal subversion.

|Mar 13, 2026
Pan-tumor activity of olomorasib, a next-generation KRAS G12C inhibitor in KRAS G12C-mutant advanced solid tumors: a first-in-human study.

Yonina R Murciano-Goroff, Antoine Hollebecque, Rebecca S Heist

|Oct 11, 2025
Modeling response to the KRAS-G12C inhibitor AZD4625 in KRASG12C NSCLC patient-derived xenografts reveals insights into primary resistance mechanisms.

Joshua C Rosen, Pinjiang Cao, Nhu-An Pham

|Jul 09, 2025
Single-Agent Divarasib in Patients With KRAS G12C-Positive Non-Small Cell Lung Cancer: Long-Term Follow-Up of a Phase I Study.

Adrian G Sacher, Wilson H Miller, Manish R Patel

|May 28, 2025
Molecular determinants of sotorasib clinical efficacy in KRASG12C-mutated non-small-cell lung cancer.

Ferdinandos Skoulidis, Bob T Li, Adrianus Johannes de Langen

|Jul 12, 2024
Circulating Tumor DNA Dynamics Reveal KRAS G12C Mutation Heterogeneity and Response to Treatment with the KRAS G12C Inhibitor Divarasib in Solid Tumors.

Yoonha Choi, Neekesh V Dharia, Tomi Jun

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Frequent Collaborators

2 joint publications

Julie Chang

2 joint publications

Jennifer L Schutzman

2 joint publications

Tomi Jun

2 joint publications

Jayesh Desai