Guillaume Mata

11PUBLICATIONS
12CO-AUTHORS
Biologically active moleculesMolecular targetsChemical and thermal processes in energy and combustionCheminformatics and quantitative structure-activity relationshipsMain group metal chemistry
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Publications (11)

|Jul 27, 2026
Discovery of a Potent, Orally Bioavailable Small-Molecule Inhibitor of Wildtype KIT with Exceptionally High Kinome Selectivity.

|Jun 05, 2026
Discovery of Casdatifan, Part II: A Potent and Orally Bioavailable Inhibitor of Hypoxia Inducible Factor-2α.

|Apr 29, 2026
Discovery of Casdatifan, Part I: Design and Characterization of Tetrahydroquinoline Inhibitors of Hypoxia-Inducible Factor-2α.

|Jan 13, 2025
Stereodivergent Synthesis of the Vicinal Difluorinated Tetralin of Casdatifan Enabled by Ru-Catalyzed Transfer Hydrogenation.

Guillaume Mata, Artur K Mailyan, Jeremy Fournier

|Oct 21, 2021
Design, Synthesis, and Structure-Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ).

Guillaume Mata, Dillon H Miles, Samuel L Drew

|Sep 01, 2020
Discovery of Potent and Selective PI3Kγ Inhibitors.

Samuel L Drew, Rhiannon Thomas-Tran, Joel W Beatty

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Frequent Collaborators

5 joint publications

Barry M Trost

5 joint publications

Kenneth V Lawson

5 joint publications

Jenna L Jeffrey

4 joint publications

Jeremy Fournier