Jinsai Shang

17PUBLICATIONS
31CO-AUTHORS
MechanobiologyMemory and attentionMolecular targetsClinical pharmacology and therapeuticsBiologically active molecules
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Publications (17)

|Apr 23, 2026
EBF2 condensates enable adipose thermogenesis through ZFP423 sequestration and epigenetic remodeling.

|Jan 21, 2026
Shifting the PPARγ conformational ensemble toward a transcriptionally repressive state improves covalent inhibitor efficacy.

Liudmyla Arifova, Brian S MacTavish, Zane Laughlin

|Dec 09, 2025
Molecular mechanism of resistance to lonafarnib conferred by mutations in the cysteine-rich region of respiratory syncytial virus fusion glycoprotein and discovery of a lonafarnib-derived antiviral PROTAC.

Qi Yang, Bao Xue, Xianjie Qiu

|Feb 28, 2025
Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states.

Brian S MacTavish, Di Zhu, Jinsai Shang

|Nov 23, 2024
Discovery of orally bioavailable SARS-CoV-2 papain-like protease inhibitor as a potential treatment for COVID-19.

Yongzhi Lu, Qi Yang, Ting Ran

|Nov 18, 2024
Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARγ.

Jinsai Shang, Douglas J Kojetin

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Frequent Collaborators

10 joint publications

Douglas J Kojetin

4 joint publications

Patrick R Griffin

4 joint publications

Xinwen Chen

3 joint publications

Qi Yang