Jamie Spangler

35PUBLICATIONS
175CO-AUTHORS
Industrial molecular engineering of nucleic acids and proteinsBiomolecular modelling and designHaematological tumoursApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Cancer therapy (excl. chemotherapy and radiation therapy)
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Publications (35)

|Jul 17, 2026
Protein engineering: status report.

|May 21, 2026
De novo design of miniproteins targeting GPCRs.

|Apr 13, 2026
Progress in Designing Cytokine Antagonist Antibodies for Cancer Therapy.

Henry McEacheron, Giulia Nisita, Peiying Liu

|Feb 06, 2026
The ancestral haplotype of P2RX5 yields a B-cell surface marker and a multi-lineage immunotherapy target.

Zhiwei Ang, Annette Castro, Luca Paruzzo

|Nov 20, 2025
Dynamics and variegation in the Treg response to Interleukin-2.

Kumba Seddu, Kaitavjeet Chowdhary, Molly Henderson

|Aug 11, 2025
Temporal optimization of CD25-biased IL-2 agonists and immune checkpoint blockade leads to synergistic anticancer activity despite robust regulatory T cell expansion.

Irfan Baki Kilic, Petra Weberova, Derek VanDyke

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Frequent Collaborators

3 joint publications

Huilin Yang

3 joint publications

David Baker

3 joint publications

K Christopher Garcia

2 joint publications

Christina S Savvides