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Lars Engstrom

6PUBLICATIONS

81CO-AUTHORS

Molecular targetsGene and molecular therapy

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Publications (6)

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|Jul 22, 2025

Combination of the MTA-Cooperative PRMT5 Inhibitor BMS-986504 and KRAS Inhibitors Is an Effective Treatment Strategy for MTAP-Deleted KRAS-Mutant Pancreatic Cancer.

Kristina Drizyte-Miller, Lars D Engstrom, Jeffrey A Klomp

|Jan 13, 2025

Impact of Co-mutations and Transcriptional Signatures in Non-Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial.

Marcelo V Negrao, Alvaro G Paula, David Molkentine

|Jun 21, 2024

The SOS1 Inhibitor MRTX0902 Blocks KRAS Activation and Demonstrates Antitumor Activity in Cancers Dependent on KRAS Nucleotide Loading.

Niranjan Sudhakar, Larry Yan, Fadia Qiryaqos

|Aug 08, 2023

MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer.

Lars D Engstrom, Ruth Aranda, Laura Waters

|Oct 10, 2022

Anti-tumor efficacy of a potent and selective non-covalent KRAS<sup>G12D</sup> inhibitor.

Jill Hallin, Vickie Bowcut, Andrew Calinisan

|Mar 16, 2021

The KRAS<sup>G12C</sup> Inhibitor MRTX849 Reconditions the Tumor Immune Microenvironment and Sensitizes Tumors to Checkpoint Inhibitor Therapy.

David M Briere, Shuai Li, Andrew Calinisan

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Frequent Collaborators

6 joint publications

Jill Hallin

5 joint publications

James G Christensen

4 joint publications

David M Briere

4 joint publications

Laura Waters

4 joint publications

Peter Olson

3 joint publications

Laura Hover

3 joint publications

J David Lawson

3 joint publications

Christopher R Smith

3 joint publications

Matthew A Marx

3 joint publications

Andrew Calinisan

Frequent Collaborators

6 joint publications

Jill Hallin

5 joint publications

James G Christensen

4 joint publications

David M Briere

4 joint publications

Laura Waters

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