Alexander James Silver

16PUBLICATIONS
119CO-AUTHORS
Haematological tumoursMolecular targetsEpigenetics (incl. genome methylation and epigenomics)Cardiology (incl. cardiovascular diseases)Gene expression (incl. microarray and other genome-wide approaches)
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Publications (16)

|Apr 10, 2026
Mutation-specific impairment of TET2 and DNMT3A enzymatic activity predicts clonal hematopoiesis disease risk.

Yash Pershad, Kun Zhao, Joseph C Van Amburg

|Aug 28, 2024
Loss-of-function mutations in Dnmt3a and Tet2 lead to accelerated atherosclerosis and concordant macrophage phenotypes.

Philipp J Rauch, Jayakrishnan Gopakumar, Alexander J Silver

|Aug 21, 2024
Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies.

Christian T Meyer, Brianna N Smith, Jing Wang

|Apr 25, 2024
Repair of leukemia-associated single nucleotide variants via interallelic gene conversion.

Alexander James Silver, Donovan J Brown, Sarah D Olmstead

|Mar 29, 2024
Solid Organ Transplant Recipients Exhibit More TET2-Mutant Clonal Hematopoiesis of Indeterminate Potential Not Driven by Increased Transplantation Risk.

Alexander J Silver, Caitlyn Vlasschaert, Taralynn Mack

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