Lingling Yang

7PUBLICATIONS
3CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMolecular targetsBiologically active molecules
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Publications (7)

|May 17, 2026
X-ray Crystallography-Guided Discovery of a Potent Dual-Pocket Competitive SIRT5 Inhibitor against Sepsis-Associated AKI.

|Feb 18, 2026
A Novel CSN5 Inhibitor Drives Tumor-Intrinsic PD-L1 Degradation and Exerts Direct Antitumor Efficacy in Triple-Negative Breast Cancer.

Yanjun Wang, Hui Lei, Wenyi Liu

|Mar 07, 2025
Discovery of New Azaindole Metallo-Deubiquitinase CSN5 Inhibitors.

Pengcheng Lei, Yu-Hang Yan, Yingying Jiang

|Aug 12, 2024
Discovering New Metallo-Deubiquitinase CSN5 Inhibitors by a Non-Catalytic Activity Assay Platform.

Yu-Hang Yan, Liu-Liu Wei, Jing-Wei Wu

|Oct 04, 2023
Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-β-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding.

Yu-Hang Yan, Ting-Ting Zhang, Rong Li

|Aug 09, 2023
Structure-Activity Relationship Studies of 2,4,5-Trisubstituted Pyrimidine Derivatives Leading to the Identification of a Novel and Potent Sirtuin 5 Inhibitor against Sepsis-Associated Acute Kidney Injury.

Luohe Mou, Lina Yang, Shuyan Hou

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Frequent Collaborators

6 joint publications

Guo-Bo Li

2 joint publications

Liang Ma

1 joint publications

Shangshang Qin