Melissa B Pappalardi

4PUBLICATIONS
47CO-AUTHORS
Nanoscale characterisationMolecular targetsGene and molecular therapy
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Publications (4)

|Jul 21, 2026
SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry.

|Jul 05, 2022
PRC2-Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1-Targeted Therapy via Enhanced Viral Mimicry.

Amish J Patel, Sarah Warda, Jesper L V Maag

|Jun 02, 2022
Chromosome-specific retention of cancer-associated DNA hypermethylation following pharmacological inhibition of DNMT1.

Ashley K Wiseman, Rochelle L Tiedemann, Huihui Fan

|Nov 18, 2021
Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia.

Melissa B Pappalardi, Kathryn Keenan, Mark Cockerill

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Frequent Collaborators

3 joint publications

Michael T McCabe

2 joint publications

John R Horton

2 joint publications

Rab K Prinjha

2 joint publications

Peter A Jones