David G McFadden

8PUBLICATIONS
38CO-AUTHORS
Molecular targetsMedical virologyCancer geneticsPredictive and prognostic markersCancer diagnosis
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (8)

|Jul 14, 2026
CDK8 inhibition induces Mediator trapping and impairment of the EWSR1::FLI1 transcriptional program in Ewing sarcoma.

|Jul 10, 2026
Ultramutagenesis through combined Msh2 depletion and proofreading-deficient DNA polymerase ε expression enhances small molecule target identification in forward genetic screens.

|Jul 03, 2026
Loss of heterozygosity exposes germline mutations in complex I and drives Warburg metabolism in oncocytic carcinoma of the thyroid.

|Dec 22, 2025
Loss of heterozygosity exposes germline mutations in complex I and drives Warburg metabolism in oncocytic carcinoma of the thyroid.

Celia de la Calle Arregui, Anderson R Frank, Kelvin Mun

|Nov 18, 2024
Endogenous EWSR1-FLI1 degron alleles enable control of fusion oncoprotein expression in tumor cell lines and xenografts.

James H McGinnis, Alberto Bremauntz Enriquez, Florentina Vandiver

|Jan 25, 2024
Forward Genetic Screens Identify Mechanisms of Resistance to Small-Molecule Lactate Dehydrogenase Inhibitors.

Anderson R Frank, Florentina Vandiver, David G McFadden

Pageof 2

Frequent Collaborators

4 joint publications

Anderson R Frank

3 joint publications

Jiwoong Kim

3 joint publications

Yang Xie

3 joint publications

Noelle Williams