David G McFadden

9PUBLICATIONS
38CO-AUTHORS
Medical virologyMolecular targetsCancer geneticsPredictive and prognostic markersCancer diagnosis
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Publications (9)

|Sep 11, 2026
Ultramutagenesis through Combined Msh2 Depletion and Proofreading-Deficient DNA Polymerase ε Expression Enhances Small-Molecule Target Identification in Forward Genetic Screens.

|Jul 14, 2026
CDK8 inhibition induces Mediator trapping and impairment of the EWSR1::FLI1 transcriptional program in Ewing sarcoma.

|Jul 10, 2026
Ultramutagenesis through combined Msh2 depletion and proofreading-deficient DNA polymerase ε expression enhances small molecule target identification in forward genetic screens.

|Jul 03, 2026
Loss of heterozygosity exposes germline mutations in complex I and drives Warburg metabolism in oncocytic carcinoma of the thyroid.

|Dec 22, 2025
Loss of heterozygosity exposes germline mutations in complex I and drives Warburg metabolism in oncocytic carcinoma of the thyroid.

Celia de la Calle Arregui, Anderson R Frank, Kelvin Mun

|Nov 18, 2024
Endogenous EWSR1-FLI1 degron alleles enable control of fusion oncoprotein expression in tumor cell lines and xenografts.

James H McGinnis, Alberto Bremauntz Enriquez, Florentina Vandiver

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Frequent Collaborators

4 joint publications

Anderson R Frank

3 joint publications

Juan Manuel Povedano

3 joint publications

Jiwoong Kim

3 joint publications

Yang Xie