Sebastian Mathea

17PUBLICATIONS

64CO-AUTHORS

Molecular targetsProteins and peptidesCheminformatics and quantitative structure-activity relationshipsPharmacogenomicsInstrumental methods (excl. immunological and bioassay methods)

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Publications (17)

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|Jun 18, 2026

Structure-Based Design, Synthesis, and Evaluation of Novel Ponatinib Derivatives With a Significantly Altered Selectivity Profile.

|Jun 12, 2026

The structural basis for LRRK2's activation and autoinhibition.

|May 26, 2026

Identification and Validation of 3-Cyano-Quinoline Ligands Targeting Integrin-Linked Kinase (ILK).

|May 01, 2026

Discovery and Development of a Potent LIMK2 Isoform-Specific Degrader.

|Sep 04, 2025

Selectivity profiles and substrate recognition of Rab-phosphorylating kinases.

Deep Chatterjee, Verena Dederer, Landon Vu Nguyen

|Jul 02, 2025

Covalent Targeting Leads to the Development of a LIMK1 Isoform-Selective Inhibitor.

Sebastian Mandel, Thomas Hanke, Niall Prendiville

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Frequent Collaborators

11 joint publications

Stefan Knapp

Thomas Hanke

Susanne Müller

Martin-Peter Schwalm

Verena Dederer

Benedict-Tilman Berger

Andres E Leschziner

Marta Sanz-Murillo

Samara Reck-Peterson

Sandra Röhm

Frequent Collaborators

11 joint publications

Stefan Knapp

6 joint publications

Thomas Hanke

6 joint publications

Susanne Müller

5 joint publications

Martin-Peter Schwalm