Jef K De Brabander

14PUBLICATIONS
35CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMolecular targetsToxicology (incl. clinical toxicology)Characterisation of biological macromoleculesMedical devices
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Publications (14)

|Jun 03, 2024
Thiophenyl Derivatives of Nicotinamide Are Metabolized by the NAD Salvage Pathway into Unnatural NAD Derivatives That Inhibit IMPDH and Are Toxic to Peripheral Nerve Cancers.

Panayotis C Theodoropoulos, Holly H Guo, Wentian Wang

|May 28, 2024
Discovery and Optimization of N-Arylated Tetracyclic Dicarboximides That Target Primary Glioma Stem-like Cells.

Hua-Yu Wang, Thu P Nguyen, Alex C Sternisha

|Oct 24, 2023
Structural insights for selective disruption of Beclin 1 binding to Bcl-2.

Yun-Zu Pan, Qiren Liang, Diana R Tomchick

|Feb 22, 2023
Evaluation of the efficacy of the hypocretin/orexin receptor agonists TAK-925 and ARN-776 in narcoleptic orexin/tTA; TetO-DTA mice.

Yu Sun, Alok Ranjan, Ryan Tisdale

|Sep 15, 2022
Novel Bcl-2 Inhibitors Selectively Disrupt the Autophagy-Specific Bcl-2-Beclin 1 Protein-Protein Interaction.

Xiaonan Dong, Qiren Liang, Yun-Zu Pan

|May 25, 2022
Molecular mechanism of the wake-promoting agent TAK-925.

Jie Yin, Yanyong Kang, Aaron P McGrath

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Frequent Collaborators

4 joint publications

Deepak Nijhawan

3 joint publications

Daniel M Rosenbaum

2 joint publications

Joseph M Ready

2 joint publications

Mack Flinspach