Richard Mackman

13PUBLICATIONS
50CO-AUTHORS
Obstetrics and gynaecologyProteins and peptidesPharmacogenomicsMolecular targetsGene and molecular therapy
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Publications (13)

|Jun 27, 2025
Pharmacokinetics and Metabolism of Broad-Spectrum Antivirals Remdesivir and Obeldesivir with a Consideration to Metabolite GS-441524: Same, Similar, or Different?

Darius Babusis, Cynthia Kim, Jesse Yang

|Jul 17, 2024
Discovery of GS-7682, a Novel 4'-Cyano-Modified <i>C</i>-Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys.

Dustin S Siegel, Hon C Hui, Jared Pitts

|Aug 19, 2023
Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys.

Richard L Mackman, Rao V Kalla, Darius Babusis

|Mar 22, 2022
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice.

Alexandra Schäfer, David R Martinez, John J Won

|Mar 16, 2022
Phosphoramidate Prodrugs Continue to Deliver, The Journey of Remdesivir (GS-5734) from RSV to SARS-CoV-2.

Richard L Mackman

|Dec 30, 2021
Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection.

Meghan S Vermillion, Eisuke Murakami, Bin Ma

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Frequent Collaborators

4 joint publications

Darius Babusis

3 joint publications

Roy Bannister

2 joint publications

Brian E Schultz

2 joint publications

Timothy P Sheahan