Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Richard Mackman

13PUBLICATIONS

50CO-AUTHORS

Obstetrics and gynaecologyProteins and peptidesPharmacogenomicsMolecular targetsGene and molecular therapy

Featured researcher

Get your video featured.

Publish with JoVE

Featured researcher

Get your video featured.

Publish with JoVE

Publications (13)

Sort by Publication Date:

|Jun 27, 2025

Pharmacokinetics and Metabolism of Broad-Spectrum Antivirals Remdesivir and Obeldesivir with a Consideration to Metabolite GS-441524: Same, Similar, or Different?

Darius Babusis, Cynthia Kim, Jesse Yang

|Jul 17, 2024

Discovery of GS-7682, a Novel 4'-Cyano-Modified <i>C</i>-Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys.

Dustin S Siegel, Hon C Hui, Jared Pitts

|Aug 19, 2023

Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys.

Richard L Mackman, Rao V Kalla, Darius Babusis

|Mar 22, 2022

Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice.

Alexandra Schäfer, David R Martinez, John J Won

|Mar 16, 2022

Phosphoramidate Prodrugs Continue to Deliver, The Journey of Remdesivir (GS-5734) from RSV to SARS-CoV-2.

Richard L Mackman

|Dec 30, 2021

Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection.

Meghan S Vermillion, Eisuke Murakami, Bin Ma

Pageof 3

Frequent Collaborators

4 joint publications

Darius Babusis

3 joint publications

Roy Bannister

2 joint publications

Brian E Schultz

2 joint publications

Timothy P Sheahan

2 joint publications

Eisuke Murakami

2 joint publications

Jared Pitts

2 joint publications

Bin Ma

2 joint publications

Joy Y Feng

2 joint publications

Jason K Perry

2 joint publications

Ralph S Baric

Frequent Collaborators

4 joint publications

Darius Babusis

3 joint publications

Roy Bannister

2 joint publications

Brian E Schultz

2 joint publications

Timothy P Sheahan

Top Related Videos

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors

Published on : Apr 09, 2014

Engineering Antiviral Agents <em>via</em> Surface Plasmon Resonance

Engineering Antiviral Agents <em>via</em> Surface Plasmon Resonance

Published on : Jun 14, 2022

Development of Cell-type specific anti-HIV gp120 aptamers for siRNA delivery

Development of Cell-type specific anti-HIV gp120 aptamers for siRNA delivery

Published on : Jun 23, 2011

See more related videos

Top Related Videos

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors

Published on : Apr 09, 2014

Engineering Antiviral Agents <em>via</em> Surface Plasmon Resonance

Engineering Antiviral Agents <em>via</em> Surface Plasmon Resonance

Published on : Jun 14, 2022

Development of Cell-type specific anti-HIV gp120 aptamers for siRNA delivery

Development of Cell-type specific anti-HIV gp120 aptamers for siRNA delivery

Published on : Jun 23, 2011

See more related videos