Guo Chen

10PUBLICATIONS
16CO-AUTHORS
Molecular targetsCancer cell biologyHaematological tumoursCancer therapy (excl. chemotherapy and radiation therapy)
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Publications (10)

|Sep 15, 2026
Targeting the PRMT5-CBX8 axis overcomes dual barriers of CD8⁺ T cell exclusion and tumor stemness for sensitizing TNBC to anti-PD-1 therapy.

|Jun 20, 2026
Choline metabolism drives metastasis in BRCA1-deficient ovarian cancers by activating FAM3C.

|Oct 06, 2025
Non canonical BRCA1 promotes cell survival via modulating PARP13-mediated SEC61G mRNA decay.

Binghe Sun, Yuting Li, Yue Wu

|Mar 04, 2025
Natural product Pulsatilla saponin D sensitizes BRCA-proficient ovarian cancers to PARP inhibitors through inhibiting homologous recombination repair.

Shengbin Lin, Binghe Sun, Yin Zhu

|Aug 24, 2023
Targeting CK2-mediated phosphorylation of p53R2 sensitizes BRCA-proficient cancer cells to PARP inhibitors.

Cong Wang, Ling Tian, Qiang He

|Jan 19, 2023
A novel Mcl-1 inhibitor synergizes with venetoclax to induce apoptosis in cancer cells.

Tianming Zhao, Qiang He, Shurong Xie

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Frequent Collaborators

2 joint publications

Yongzhu Liu

2 joint publications

Caiyong Lai

1 joint publications

Qi Qi

1 joint publications

Shuang Peng