Yan Zhang

29PUBLICATIONS
25CO-AUTHORS
Biomolecular modelling and designMedical parasitologyCheminformatics and quantitative structure-activity relationshipsBiologically active moleculesMolecular targets
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Publications (29)

|Jul 06, 2026
Landscaping the Nitazene Scaffold to Identify Novel Mu-Opioid Receptor Modulators: From Molecular Design and Chemical Synthesis to Pharmacological Profiling.

|Apr 30, 2026
Structural Determinants of μ-Opioid Receptor Antagonism and Respiratory Liability in Phenylfentanyl Analogues.

|Jan 22, 2026
Investigating the Landscape of C6-Azaindole Side Chain on the Epoxymorphinan Skeleton via the Nitrogen Walk Concept: A Strategy to Enhance Drug-Like Properties.

Logan Neel, Hongguang Ma, Ahmed Reda

|Nov 03, 2025
Design, Syntheses, and Pharmacological Evaluations of Core Ring Expanded Fentanyl Analogues as Potential Counteracting Agents Against Fentanyl Induced Respiratory Depression.

Abeje A Silte, Ennian Li, Balaji S Kale

|May 26, 2025
Exploring substitution effects on the potential dominant conformations of NBF derivatives leading to functional conversion at the mu opioid receptor.

Ennian Li, Ahmed Reda, Hongguang Ma

|Dec 19, 2024
Discovery of 6α-Thiazolylcarboxamidonaltrexamine Derivative (NTZ) as a Potent and Central Nervous System Penetrant Opioid Receptor Modulator with Drug-like Properties for Potential Treatment of Opioid Use Disorder.

Boshi Huang, Hongguang Ma, Piyusha P Pagare

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Frequent Collaborators

11 joint publications

Piyusha P Pagare

4 joint publications

Celsey M St Onge

3 joint publications

Abeje A Silte

3 joint publications

Mengchu Li