David J Segal

16PUBLICATIONS
79CO-AUTHORS
Micro- and nanosystemsGenome structure and regulationAnimal growth and developmentPredictive and prognostic markersEpigenetics (incl. genome methylation and epigenomics)
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Publications (16)

|Jul 16, 2026
Ionizable Silyl Lipids with Distinct Membrane Fluidity and mRNA Delivery Profiles.

|Dec 03, 2025
A split luciferase biosensing platform for detection and imaging of chromatin loops in individual live cells.

Nicholas G Heath, J Antonio Gomez, Sean P McGinty

|Jul 21, 2025
A preclinical pig model of Angelman syndrome mirrors the early developmental trajectory of the human condition.

Luke S Myers, Sarah G Christian, Sean Simpson

|Feb 20, 2025
De-novo DNA Methylation of Bivalent Promoters Induces Gene Activation through PRC2 Displacement.

Henriette O'Geen, Alina Mihalovits, Benjamin D Brophy

|Apr 08, 2024
Integration of CTCF Loops, Methylome, and Transcriptome in Differentiating LUHMES as a Model for Imprinting Dynamics of the 15q11-q13 Locus in Human Neurons.

Orangel J Gutierrez Fugon, Osman Sharifi, Nicholas G Heath

|Jan 10, 2023
Dr.Nod: computational framework for discovery of regulatory non-coding drivers in tissue-matched distal regulatory elements.

Marketa Tomkova, Jakub Tomek, Julie Chow

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Frequent Collaborators

3 joint publications

Marketa Tomkova

3 joint publications

Henriette O'Geen

2 joint publications

Jill L Silverman

2 joint publications

Luis G Carvajal-Carmona