Simon J Cook

14PUBLICATIONS
28CO-AUTHORS
Proteomics and intermolecular interactions (excl. medical proteomics)Molecular targetsGene and molecular therapyImmunogenetics (incl. genetic immunology)Innate immunity
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Publications (14)

|Nov 17, 2025
RAF inhibitors activate the integrated stress response by direct activation of GCN2.

Rebecca Gilley, Andrew M Kidger, Graham Neill

|Dec 11, 2024
Second MEK Inhibitor Shows Promise in Neurofibromatosis Type 1 With Symptomatic Plexiform Neurofibromas Signaling Hope for Other RASopathies.

Simon J Cook

|Feb 21, 2024
Reporter cell lines to screen for inhibitors or regulators of the KRAS-RAF-MEK1/2-ERK1/2 pathway.

Laura Weatherdon, Kate Stuart, Megan Cassidy

|Apr 05, 2023
ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1.

Kathryn Balmanno, Andrew M Kidger, Dominic P Byrne

|Oct 21, 2022
Escape from G1 arrest during acute MEK inhibition drives the acquisition of drug resistance.

Prasanna Channathodiyil, Kieron May, Anne Segonds-Pichon

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