János Éles

7PUBLICATIONS
18CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsBiologically active moleculesBiomolecular modelling and designChemical and thermal processes in energy and combustion
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Publications (7)

|Jan 22, 2026
The Discovery of RGH-706, a Highly Efficacious MCH1 Receptor Antagonist, for the Treatment of Obesity and Insatiable Hunger.

Gyula Beke, András Boros, György M Keserű

|Jul 17, 2025
Continuous-flow synthesis of 1,4,6,7-tetrahydro-5H-[1,2,3]triazolo[4,5-c]pyridines towards key intermediates of clinical candidates JNJ-54175446 and zanvipixant (JNJ-55308942) with antidepressant activity.

Zsolt Fülöp, Péter Bana, István Greiner

|Apr 18, 2024
Transaminase-catalysis to produce trans-4-substituted cyclohexane-1-amines including a key intermediate towards cariprazine.

Emese Farkas, Péter Sátorhelyi, Zoltán Szakács

|Mar 20, 2024
Novel-Type GABAB PAMs: Structure-Activity Relationship in Light of the Protein Structure.

Balázs Krámos, Zsuzsa Hadady, Attila Makó

|Feb 23, 2024
Discovery of Novel Steroid-Based Histamine H3 Receptor Antagonists/Inverse Agonists.

István Ledneczki, Pál Tapolcsányi, Eszter Gábor

|Nov 21, 2023
Optimization of Novel α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulators and the Discovery of a Preclinical Development Candidate Molecule (RGH-560).

István Ledneczki, Zsolt Némethy, Katalin Dudásné Molnár

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Frequent Collaborators

5 joint publications

István Greiner

2 joint publications

Zoltán Szakács

2 joint publications

István Ledneczki

2 joint publications

Balázs Krámos