Sebastian M Fica

7PUBLICATIONS
66CO-AUTHORS
Haematological tumoursSequence analysisNeurology and neuromuscular diseasesPolymerisation mechanismsEpigenetics (incl. genome methylation and epigenomics)
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Publications (7)

|Oct 01, 2026
Somatic DDX41 mutations confer neomorphic splicing activity in the pathogenesis of myelodysplastic neoplasms.

|Jan 14, 2025
RNA splicing: a split consensus reveals two major 5' splice site classes.

Matthew T Parker, Sebastian M Fica, Gordon G Simpson

|Jul 11, 2024
De novo variants in the RNU4-2 snRNA cause a frequent neurodevelopmental syndrome.

Yuyang Chen, Ruebena Dawes, Hyung Chul Kim

|Dec 20, 2023
Monovalent metal ion binding promotes the first transesterification reaction in the spliceosome.

Jana Aupič, Jure Borišek, Sebastian M Fica

|Oct 03, 2023
Inter-species association mapping links splice site evolution to METTL16 and SNRNP27K.

Matthew T Parker, Sebastian M Fica, Geoffrey J Barton

|Mar 06, 2021
psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation.

Lisa M Strittmatter, Charlotte Capitanchik, Andrew J Newman

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Frequent Collaborators

2 joint publications

Kiyoshi Nagai

2 joint publications

Matthew T Parker

2 joint publications

Gordon G Simpson

1 joint publications

Chris Oubridge