Sebastian M Fica

6PUBLICATIONS
61CO-AUTHORS
Sequence analysisNeurology and neuromuscular diseasesPolymerisation mechanismsEpigenetics (incl. genome methylation and epigenomics)Reaction engineering (excl. nuclear reactions)
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Publications (6)

|Jan 14, 2025
RNA splicing: a split consensus reveals two major 5' splice site classes.

Matthew T Parker, Sebastian M Fica, Gordon G Simpson

|Jul 11, 2024
De novo variants in the RNU4-2 snRNA cause a frequent neurodevelopmental syndrome.

Yuyang Chen, Ruebena Dawes, Hyung Chul Kim

|Dec 20, 2023
Monovalent metal ion binding promotes the first transesterification reaction in the spliceosome.

Jana Aupič, Jure Borišek, Sebastian M Fica

|Oct 03, 2023
Inter-species association mapping links splice site evolution to METTL16 and SNRNP27K.

Matthew T Parker, Sebastian M Fica, Geoffrey J Barton

|Mar 06, 2021
psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation.

Lisa M Strittmatter, Charlotte Capitanchik, Andrew J Newman

|Feb 02, 2019
A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation.

Sebastian M Fica, Chris Oubridge, Max E Wilkinson

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