Joseph S Brunzelle

6PUBLICATIONS
57CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsNeurosciences not elsewhere classifiedGenome structure and regulationAtomic and molecular physicsOrganic chemical synthesis
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Publications (6)

|Jan 22, 2026
S‑Adenosylhomocysteine Analogs Selectively Suppress Pan-Coronavirus Replication by Inhibition of nsp14 Methyltransferase.

Monica Rosas-Lemus, Sudhakar Athe, George Minasov

|Aug 26, 2024
Torsional Twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains.

Monica Rosas-Lemus, George Minasov, Joseph S Brunzelle

|Mar 17, 2022
The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication.

Hossein Davarinejad, Yi-Chun Huang, Benoit Mermaz

|Aug 26, 2021
Structure of an AMPK complex in an inactive, ATP-bound state.

Yan Yan, Somnath Mukherjee, Kaleeckal G Harikumar

|Jun 16, 2021
Mn2+ coordinates Cap-0-RNA to align substrates for efficient 2'-O-methyl transfer by SARS-CoV-2 nsp16.

George Minasov, Monica Rosas-Lemus, Ludmilla Shuvalova

|Sep 30, 2020
High-resolution structures of the SARS-CoV-2 2'-O-methyltransferase reveal strategies for structure-based inhibitor design.

Monica Rosas-Lemus, George Minasov, Ludmilla Shuvalova

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