Hugo M Vargas
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5CO-AUTHORS
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Publications (5)
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|Aug 23, 2025
Delayed Repolarization Caused by hERG Block With Different Drug Modalities Can Be Detected in Stem Cell-Derived Cardiomyocytes: Incubation Time Matters.Yusheng Qu, Wei Guo, Bin Wu
|May 21, 2025
Restraint-Based ECG and Arterial Pressure Assessment Do Not Reliably Detect Drug Induced QTc Prolongation and Hypotension: Evidence From Case Studies.Kim A Henderson, Nicholas Ether, Hugo M Vargas
|Feb 16, 2024
Scientific Review of the Proarrhythmic Risks of Oligonucleotide Therapeutics: Are Dedicated ICH S7B/E14 Studies Needed for Low-Risk Modalities?Yusheng Qu, Kim A Henderson, Tod A Harper
|Nov 12, 2022
Evaluation of levocetirizine in beagle dog and cynomolgus monkey telemetry assays: Defining the no QTc effect profile by timepoint and concentration-QTc analysis.Michael J Engwall, Joel Baublits, Fiona A Chandra
|Sep 01, 2020
Time for a Fully Integrated Nonclinical-Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective.Hugo M Vargas, Michael G Rolf, Todd A Wisialowski
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