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Edcon Chang

7PUBLICATIONS

26CO-AUTHORS

Biomolecular modelling and designCheminformatics and quantitative structure-activity relationshipsBiomaterials

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Publications (7)

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|Jan 08, 2026

Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase.

Irene Georgiou, Colin Robinson, Sean N O'Byrne

|Sep 14, 2024

Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2.

Han Wee Ong, Xuan Yang, Jeffery L Smith

|Jul 03, 2024

More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-<i>a</i>]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication.

Han Wee Ong, Xuan Yang, Jeffery L Smith

|Feb 14, 2024

Tryptanthrin Analogs Substoichiometrically Inhibit Seeded and Unseeded Tau4RD Aggregation.

Ellie I James, David W Baggett, Edcon Chang

|Oct 30, 2023

Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-<i>a</i>]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A.

Xuan Yang, Han Wee Ong, Rebekah J Dickmander

|Sep 20, 2023

Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors.

Nicole L Inniss, Ján Kozic, Fengling Li

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Frequent Collaborators

4 joint publications

Han Wee Ong

4 joint publications

Alison D Axtman

4 joint publications

Timothy M Willson

2 joint publications

Jeffery L Smith

2 joint publications

David H Drewry

2 joint publications

Rafael M Couñago

1 joint publications

Xuan Yang

1 joint publications

Rebekah J Dickmander

1 joint publications

Duncan E Scott

1 joint publications

Erik Andris

Frequent Collaborators

4 joint publications

Han Wee Ong

4 joint publications

Alison D Axtman

4 joint publications

Timothy M Willson

2 joint publications

Jeffery L Smith

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