Matthew N Gaynes
6PUBLICATIONS
11CO-AUTHORS
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Publications (6)
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|Dec 01, 2025
Structure and Mechanism of Avermitilol Synthase, a Sesquiterpene Cyclase That Generates a Highly Strained 6-6-3 Tricyclic Alcohol.Matthew N Gaynes, Kristin R Osika, David W Christianson
|Oct 17, 2025
Cryo-EM Structure of the Cyclase Domain and Evaluation of Substrate Channeling in a Bifunctional Class II Terpene Synthase.Matthew N Gaynes, Kollin Schultz, Eliott S Wenger
|Sep 02, 2025
Cryo-EM Structure of the Cyclase Domain and Evaluation of Substrate Channeling in a Bifunctional Class II Terpene Synthase.Matthew N Gaynes, Kollin Schultz, Eliott S Wenger
|Feb 24, 2025
Crystal Structure and Catalytic Mechanism of Drimenol Synthase, a Bifunctional Terpene Cyclase-Phosphatase.Kristin R Osika, Matthew N Gaynes, David W Christianson
|Feb 13, 2025
Exploring Alternative Zinc-Binding Groups in Histone Deacetylase (HDAC) Inhibitors Uncovers <b>DS-103</b> as a Potent Ethylhydrazide-Based HDAC Inhibitor with Chemosensitizing Properties.Daniel Stopper, Lukas Biermann, Paris R Watson
|Nov 11, 2024
Structure and Function of Sabinene Synthase, a Monoterpene Cyclase That Generates a Highly Strained [3.1.0] Bicyclic Product.Matthew N Gaynes, Kristin R Osika, David W Christianson
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Frequent Collaborators
7 joint publications
David W Christianson
3 joint publications
Kristin R Osika
2 joint publications
Eliott S Wenger
2 joint publications
Ronen Marmorstein
1 joint publications
Daniel Stopper
1 joint publications
Lais Pessanha de Carvalho
1 joint publications
Daniel Ramsbeck
1 joint publications
Jana Held
1 joint publications
Matthias U Kassack
1 joint publications
Finn K Hansen
