Christian Landles

12PUBLICATIONS
33CO-AUTHORS
Cardiology (incl. cardiovascular diseases)Critical heritage, museum and archive studiesNeurogeneticsEpigenetics (incl. genome methylation and epigenomics)Central nervous system
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (12)

|Aug 04, 2026
Enhancing the detection of HTT1a with neoepitope antibodies in mouse models of Huntington's disease.

|Mar 18, 2026
Lowering the HTT1a transcript as an effective therapy for Huntington's disease in a knockin mouse model.

Aikaterini Smaragdi Papadopoulou, Julia Alterman, Christian Landles

|Mar 18, 2026
Selective targeting of mutant huntingtin intron 1 improves rescue provided by antisense oligonucleotides in Huntington's disease mice.

Robert M Bragg, Christian Landles, Edward J Smith

|Feb 02, 2026
The HTT1a protein initiates HTT aggregation in a knock-in mouse model of Huntington's disease.

Aikaterini Smaragdi Papadopoulou, Christian Landles, Edward J Smith

|Dec 23, 2024
Mutant huntingtin protein decreases with CAG repeat expansion: implications for therapeutics and bioassays.

Christian Landles, Georgina F Osborne, Jemima Phillips

|Aug 18, 2024
Exon 1-targeting miRNA reduces the pathogenic exon 1 HTT protein in Huntington's disease models.

Marina Sogorb-Gonzalez, Christian Landles, Nicholas S Caron

Pageof 2

Frequent Collaborators

11 joint publications

Georgina Osborne

11 joint publications

Gillian P Bates

5 joint publications

Jemima Phillips

3 joint publications

Edward J Smith