Christian Landles

14PUBLICATIONS
53CO-AUTHORS
Cardiology (incl. cardiovascular diseases)Critical heritage, museum and archive studiesNeurogeneticsEpigenetics (incl. genome methylation and epigenomics)Central nervous system
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Publications (14)

|Aug 30, 2026
Human-specific sequence features in HTT exon 1 promote toxic misprocessing via splicing factor SRSF7.

|Aug 12, 2026
Blocking somatic repeat expansion and lowering huntingtin by RNAi synergize to attenuate Huntington's disease pathogenesis in mice.

|Aug 04, 2026
Enhancing the detection of HTT1a with neoepitope antibodies in mouse models of Huntington's disease.

|Mar 18, 2026
Lowering the HTT1a transcript as an effective therapy for Huntington's disease in a knockin mouse model.

Aikaterini Smaragdi Papadopoulou, Julia Alterman, Christian Landles

|Mar 18, 2026
Selective targeting of mutant huntingtin intron 1 improves rescue provided by antisense oligonucleotides in Huntington's disease mice.

Robert M Bragg, Christian Landles, Edward J Smith

|Feb 02, 2026
The HTT1a protein initiates HTT aggregation in a knock-in mouse model of Huntington's disease.

Aikaterini Smaragdi Papadopoulou, Christian Landles, Edward J Smith

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Frequent Collaborators

13 joint publications

Georgina Osborne

13 joint publications

Gillian P Bates

5 joint publications

Jemima Phillips

3 joint publications

Edward J Smith