Matthew R Groves

26PUBLICATIONS
43CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designCell development, proliferation and deathMedical parasitologyMolecular targets
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Publications (26)

|Apr 15, 2026
Ugi-Tetrazole-Derived α‑Aminomethyl Scaffolds Reveal Unexpected Binding Modes in SARS-CoV‑2 3CLpro.

Robin van der Straat, Rick Oerlemans, Yingying Cong

|Mar 26, 2026
Repurposing of Inhibitors of Plasmodial Aspartate Transcarbamoylase Toward Trypanosoma Cruzi.

Siyao Chen, Monica Cal, Queenie Mondile

|Dec 26, 2025
Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases.

Nika Sokolova, Angelina Osipyan, Lili Zhang

|Feb 12, 2025
Exploring Aspartate Transcarbamoylase: A Promising Broad-Spectrum Target for Drug Development.

Siyao Chen, Queenie Mondile, XiaoChen Du

|Aug 05, 2024
Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain.

Victor O Gawriljuk, Andre S Godoy, Rick Oerlemans

|Apr 11, 2024
Small-Molecule Allosteric Inhibitors of Human Aspartate Transcarbamoylase Suppress Proliferation of Bone Osteosarcoma Epithelial Cells.

Chao Wang, Bidong Zhang, Yingying Cong

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Frequent Collaborators

12 joint publications

Alexander S S Dömling

5 joint publications

Carsten Wrenger

3 joint publications

Kristina Haslinger

2 joint publications

Siyao Chen