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Ari J Firestone

7PUBLICATIONS

55CO-AUTHORS

Molecular targetsCheminformatics and quantitative structure-activity relationshipsBiomedical imaging

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Publications (7)

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|Feb 09, 2026

Microsatellite instable cancer cells acquire on-target resistance mutations to WRN helicase inhibitors.

Faith Fowler, Jessica Gajda, Amirhossein Mafi

|Sep 18, 2025

Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer.

Melat T Gebru, Timothy E Hoffman, Aaron Boudreau

|Jun 05, 2025

Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen.

Yunsong Tong, Kenton A Baker, Alex M Chapman

|Feb 15, 2024

Inhibition of Aurora Kinase Induces Endogenous Retroelements to Induce a Type I/III IFN Response via RIG-I.

Lisa Choy, Stephen Norris, Xiumin Wu

|Mar 06, 2023

Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis <i>In Vivo</i>.

John T Randolph, Matthew J O'Connor, Fei Han

|Apr 30, 2021

ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth.

Jarrett R Remsberg, Radu M Suciu, Noemi A Zambetti

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Frequent Collaborators

2 joint publications

Henry Yue Hin Tang

2 joint publications

Jonathan Hickson

2 joint publications

Fei Han

2 joint publications

David Stokoe

2 joint publications

Nathan J Gesmundo

2 joint publications

Jessica Gajda

2 joint publications

Nathaniel L Elsen

2 joint publications

Yunsong Tong

1 joint publications

Stephen Norris

1 joint publications

Jeffrey Settleman

Frequent Collaborators

2 joint publications

Henry Yue Hin Tang

2 joint publications

Jonathan Hickson

2 joint publications

Fei Han

2 joint publications

David Stokoe

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