Ari J Firestone
7PUBLICATIONS
55CO-AUTHORS
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Publications (7)
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|Feb 09, 2026
Microsatellite Instable Cancer Cells Acquire On-target Resistance Mutations to WRN Helicase Inhibitors.Faith Fowler, Jessica Gajda, Amirhossein Mafi
|Sep 18, 2025
Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer.Melat T Gebru, Timothy E Hoffman, Aaron Boudreau
|Jun 05, 2025
Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen.Yunsong Tong, Kenton A Baker, Alex M Chapman
|Feb 15, 2024
Inhibition of Aurora Kinase Induces Endogenous Retroelements to Induce a Type I/III IFN Response via RIG-I.Lisa Choy, Stephen Norris, Xiumin Wu
|Mar 06, 2023
Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo.John T Randolph, Matthew J O'Connor, Fei Han
|Apr 30, 2021
ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth.Jarrett R Remsberg, Radu M Suciu, Noemi A Zambetti
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Frequent Collaborators
2 joint publications
Henry Yue Hin Tang
2 joint publications
Jonathan Hickson
2 joint publications
Fei Han
2 joint publications
David Stokoe
2 joint publications
Nathan J Gesmundo
2 joint publications
Jessica Gajda
2 joint publications
Nathaniel L Elsen
2 joint publications
Yunsong Tong
1 joint publications
Stephen Norris
1 joint publications
Jeffrey Settleman
