Ladislav Vyklický

6PUBLICATIONS
34CO-AUTHORS
Genetically modified animalsNeurology and neuromuscular diseasesCharacterisation of biological macromoleculesToxicology (incl. clinical toxicology)Nanoscale characterisation
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Publications (6)

|Jan 30, 2026
Mice carrying a GluN2B protein-truncating variant have altered NMDA receptor subunit composition and their behavior recapitulates patient phenotypes.

Klevinda Fili, Viktor Kuchtiak, Eni Tomovic

|Jan 12, 2024
Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids.

Bohdan Kysilov, Viktor Kuchtiak, Barbora Hrcka Krausova

|Mar 23, 2022
Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations.

Bohdan Kysilov, Barbora Hrcka Krausova, Vojtech Vyklicky

|Sep 14, 2021
Pharmacokinetic, pharmacodynamic, and behavioural studies of deschloroketamine in Wistar rats.

Kristýna Štefková-Mazochová, Hynek Danda, Wim Dehaen

|Jul 03, 2020
Site of Action of Brain Neurosteroid Pregnenolone Sulfate at the N-Methyl-D-Aspartate Receptor.

Barbora Hrcka Krausova, Bohdan Kysilov, Jiri Cerny

|Oct 02, 2019
NMDA Receptor Opening and Closing-Transitions of a Molecular Machine Revealed by Molecular Dynamics.

Jiří Černý, Paulína Božíková, Aleš Balík

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Frequent Collaborators

5 joint publications

Jiří Černý

5 joint publications

Tereza Smejkalova

3 joint publications

Paulína Božíková

3 joint publications

Ales Balik