Carol M Manhart

7PUBLICATIONS
0CO-AUTHORS
Epigenetics (incl. genome methylation and epigenomics)Medical infection agents (incl. prions)Molecular, biological, and multi-scale communicationsMicroelectromechanical systems (MEMS)
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Publications (7)

|Dec 30, 2025
The GHKL ATPase Family as a Paradigm for MutL Homolog Function in DNA Mismatch Repair.

Jonathan M Piscitelli, Carol M Manhart

|Dec 03, 2025
Mlh1-Pms1 couples ATP-driven DNA compaction with nick-dependent endonuclease activation.

Bryce W Collingwood, Amruta N Bhalkar, Carol M Manhart

|Jan 27, 2025
The mismatch repair factor Mlh1-Pms1 uses ATP to compact and remodel DNA.

Bryce W Collingwood, Amruta N Bhalkar, Carol M Manhart

|Dec 20, 2024
Mlh1-Pms1 ATPase activity is regulated distinctly by self-generated nicks and strand discrimination signals in mismatch repair.

Jonathan M Piscitelli, Scott J Witte, Yasmine S Sakinejad

|Nov 27, 2024
Action-At-A-Distance in DNA Mismatch Repair: Mechanistic Insights and Models for How DNA and Repair Proteins Facilitate Long-Range Communication.

Bryce W Collingwood, Scott J Witte, Carol M Manhart

|Jun 25, 2024
The Mlh1-Pms1 endonuclease uses ATP to preserve DNA discontinuities as strand discrimination signals to facilitate mismatch repair.

Jonathan M Piscitelli, Scott J Witte, Yasmine S Sakinejad

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