Francesc Xavier Ruiz

13PUBLICATIONS
72CO-AUTHORS
Major global burdens of diseaseCheminformatics and quantitative structure-activity relationshipsMedical molecular engineering of nucleic acids and proteinsProteins and peptidesMedical devices
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Publications (13)

|Jul 17, 2026
Discovery of non-nucleoside inhibitors of the enterovirus D68 3D polymerase through crystallographic fragment and high-throughput biochemical screening.

|Sep 02, 2025
Crystallographic Fragment Screening of the Dengue Virus Polymerase Reveals Multiple Binding Sites for the Development of Non-nucleoside Antiflavivirals.

Manisha Saini, Jasmin C Aschenbrenner, Francesc Xavier Ruiz

|May 30, 2025
Development of enhanced HIV-1 non-nucleoside reverse transcriptase inhibitors with improved resistance and pharmacokinetic profiles.

Zhao Wang, Shawn Rumrill, Dongwei Kang

|Apr 16, 2025
Crystallographic fragment screening of the dengue virus polymerase reveals multiple binding sites for the development of non-nucleoside antiflavivirals.

Manisha Saini, Jasmin C Aschenbrenner, Francesc Xavier Ruiz

|Feb 13, 2025
Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates.

Prakash Jadhav, Xueying Liang, Ahmadullah Ansari

|Nov 05, 2024
Structure-Based Design of Covalent SARS-CoV-2 Papain-like Protease Inhibitors.

Bin Tan, Xueying Liang, Ahmadullah Ansari

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Frequent Collaborators

11 joint publications

Eddy Arnold

3 joint publications

Bin Tan

3 joint publications

Jun Wang

2 joint publications

Xiang Chi