Michael Kugler

9PUBLICATIONS
26CO-AUTHORS
Medical virologyMolecular targetsCheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designEpigenetics (incl. genome methylation and epigenomics)
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Publications (9)

|Sep 18, 2025
Structural basis for DNA break sensing by human MRE11-RAD50-NBS1 and its regulation by telomeric factor TRF2.

Yilan Fan, Filiz Kuybu, Hengjun Cui

|Dec 03, 2024
Phosphorylation-mediated conformational change regulates human SLFN11.

Michael Kugler, Felix J Metzner, Gregor Witte

|Feb 10, 2023
Identification of specific carbonic anhydrase inhibitors via in situ click chemistry, phage-display and synthetic peptide libraries: comparison of the methods and structural study.

Michael Kugler, Martin Hadzima, Rastislav Dzijak

|Jan 03, 2023
B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides.

Jindřich Fanfrlík, Jiří Brynda, Michael Kugler

|Sep 17, 2022
Mechanistic understanding of human SLFN11.

Felix J Metzner, Simon J Wenzl, Michael Kugler

|May 03, 2021
Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds.

Michael Kugler, Jan Nekvinda, Josef Holub

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Frequent Collaborators

5 joint publications

Bohumír Grüner

4 joint publications

Pavlína Řezáčová

3 joint publications

Suzan El Anwar

3 joint publications

Jiří Brynda