David R Borchelt

13PUBLICATIONS
40CO-AUTHORS
Neurology and neuromuscular diseasesPsychophysiologyMedical molecular engineering of nucleic acids and proteinsPredictive and prognostic markersMedical infection agents (incl. prions)
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Publications (13)

|Feb 17, 2026
Efficient induction of motor neuron disease in transgenic G93A SOD1 mice by prion-like seeding.

Guilian Xu, Amanda Lopez, Selma Brkic

|Jul 09, 2025
Progressive Supranuclear Palsy PERK haplotype B selectively translates DLX1 promoting tau toxicity.

Christian B Lessard, Diego Rubio-Rubio, Samantha Tolton

|Dec 11, 2023
Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease.

Yona Levites, Eric B Dammer, Yong Ran

|Sep 28, 2023
Multiple Factors Influence the Incubation Period of ALS Prion-like Transmission in SOD1 Transgenic Mice.

Jacob I Ayers, Guilian Xu, Qing Lu

|Jul 27, 2022
Modeling the Competition between Misfolded Aβ Conformers That Produce Distinct Types of Amyloid Pathology in Alzheimer's Disease.

Guilian Xu, Susan Fromholt, David R Borchelt

|May 21, 2021
Variation in the vulnerability of mice expressing human superoxide dismutase 1 to prion-like seeding: a study of the influence of primary amino acid sequence.

Jacob I Ayers, Guilian Xu, Kristy Dillon

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Frequent Collaborators

3 joint publications

Todd Golde

2 joint publications

Nicholas T Seyfried

1 joint publications

Jason Martin

1 joint publications

Lorena de Mena