Pavel Mader

8PUBLICATIONS
18CO-AUTHORS
Metabolomic chemistryMolecular targetsCharacterisation of biological macromoleculesBiomolecular modelling and designWearable materials
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Journal

Publications (8)

|Jun 27, 2026
Structure and mechanism of inhibition of lysine demethylase 2A (KDM2A) by compound 183c.

|Feb 18, 2026
Design of a Targeted Covalent Probe to Interrogate the DNA Polymerase Activity of Polθ.

Monica Bubenik, Pavel Mader, Stephen Orlicky

|Sep 08, 2025
The Discovery of RP-2119: A Potent, Selective, and Orally Bioavailable Polθ ATPase Inhibitor.

Philippe Mochirian, Robert Papp, Marie-Claude Mathieu

|May 16, 2025
Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor.

Frédéric Vallée, Matias Casás-Selves, Monica Bubenik

|Sep 20, 2022
Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ.

Monica Bubenik, Pavel Mader, Philippe Mochirian

|Sep 19, 2022
Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.

Chetan K Chana, Pierre Maisonneuve, Ganna Posternak

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Frequent Collaborators

7 joint publications

Frank Sicheri

4 joint publications

Victor Pau

3 joint publications

W Cameron Black

2 joint publications

Mike Tyers