Matthew D Troyer

6PUBLICATIONS
82CO-AUTHORS
Molecular targetsPredictive and prognostic markersClinical pharmacology and therapeuticsBiomaterialsMedical biochemistry - inorganic elements and compounds
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Publications (6)

|Aug 18, 2025
Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial.

Brittany N Flores, Seungyoon B Yu, Isaac V Cohen

|May 13, 2023
A leucine-rich repeat kinase 2 (LRRK2) pathway biomarker characterization study in patients with Parkinson's disease with and without LRRK2 mutations and healthy controls.

Maurits F J M Vissers, Matthew D Troyer, Eva Thijssen

|Feb 22, 2023
LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease.

Danna Jennings, Sarah Huntwork-Rodriguez, Maurits F J M Vissers

|Jun 08, 2022
Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson's disease.

Danna Jennings, Sarah Huntwork-Rodriguez, Anastasia G Henry

|Feb 28, 2022
Molecular architecture determines brain delivery of a transferrin receptor-targeted lysosomal enzyme.

Annie Arguello, Cathal S Mahon, Meredith E K Calvert

|Jul 26, 2020
Characterization of Fluid Biomarkers Reveals Lysosome Dysfunction and Neurodegeneration in Neuronopathic MPS II Patients.

Akhil Bhalla, Ritesh Ravi, Meng Fang

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Frequent Collaborators

3 joint publications

Anastasia G Henry

3 joint publications

Annie Arguello

3 joint publications

Kimberly Scearce-Levie

3 joint publications

Jules A A C Heuberger