Jake Lehle

6PUBLICATIONS
31CO-AUTHORS
Gene expression (incl. microarray and other genome-wide approaches)Molecular targetsMedical molecular engineering of nucleic acids and proteinsGenome structure and regulationBioavailability and ecotoxicology
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Publications (6)

|Nov 06, 2026
CODMA-A3: A Competitive Oligo-based DNA Modification Assay Applied to APOBEC Enzymes.

|Oct 10, 2026
Deciphering the Network Architecture of APOBEC3-Driven Mutagenesis in HPV-Positive Head and Neck Cancers.

|Oct 08, 2026
APOBEC3G Splicing Defects in Nonhuman Primate Models Result in Disparate Viral Mutational Profiles Relative to Humans.

|Oct 01, 2026
Deconvolution of HIV-1 Mutational Signatures Reveals Dominant and Donor-Specific APOBEC3-Associated Mutagenesis Across Anatomical Compartments.

|Oct 03, 2024
An in vitro approach reveals molecular mechanisms underlying endocrine disruptor-induced epimutagenesis.

Jake D Lehle, Yu-Huey Lin, Amanda Gomez

|Jul 11, 2023
Accelerating the alignment processing speed of the comprehensive end-to-end whole-genome bisulfite sequencing pipeline, wg-blimp.

Jake D Lehle, John R McCarrey

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Frequent Collaborators

4 joint publications

Rachael Springman-Rodriguez

4 joint publications

Diako Ebrahimi

3 joint publications

Armando Mendez

3 joint publications

Niloofar Haghjoo