Michal Hocek

71PUBLICATIONS
56CO-AUTHORS
Evolutionary computationBiologically active moleculesGlycoconjugatesCharacterisation of biological macromoleculesCell and nuclear division
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Publications (71)

|May 27, 2026
Expedient single-round selection of hyper-modified aptamer targeting insulin receptor from over-represented dually nucleobase-modified DNA libraries.

|Jan 15, 2026
Potent Competitive Inhibitors of Ecto-5'-nucleotidase (CD73) based on 6‑(Het)aryl-7-deazapurine Ribonucleoside 5'‑<i>O</i>‑Bisphosphonates.

Ugnė Šinkevičiu̅tė, Magdalena Šímová, Radek Staník

|Dec 10, 2025
Hydrophobic alkyl-linked base-modified pyrimidine and 7-deazapurine 2'-deoxyribonucleoside phosphoramidites: synthesis and application in solid-phase synthesis of modified and hypermodified oligonucleotides.

Ivana Jestřábová, Lucie Bednárová, Lenka Poštová Slavětínská

|Nov 06, 2025
Enzymatic Synthesis of Modified RNA Containing 5-Methyl- or 5-Ethylpyrimidines or Substituted 7-Deazapurines and Influence of the Modifications on Stability, Translation, and CRISPR-Cas9 Cleavage.

Tania Sanchez-Quirante, Erika Kužmová, Miguel Riopedre-Fernandez

|Sep 26, 2025
Versatile Enzymatic Approach for Truncation, Labeling, and Mutation of Nucleobase-Modified Aptamers Demonstrated on Indole-Modified β-Conglutin Aptamer.

Marek Ondruš, Pablo Alberto Franco-Urquijo, Teresa Mairal Lerga

|Sep 09, 2025
Super-Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation.

Maruthi K Pabba, Miroslav Kuba, Tomáš Kraus

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Frequent Collaborators

7 joint publications

Marek Ondruš

6 joint publications

Ciara K O'Sullivan

5 joint publications

Tomáš Kraus

5 joint publications

Radek Pohl