Alexander J Whitworth

23PUBLICATIONS
99CO-AUTHORS
PharmacogenomicsMetabolic medicinePredictive and prognostic markersToxicology (incl. clinical toxicology)Nanoscale characterisation
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Publications (23)

|Dec 24, 2025
Insights into PINK1/Parkin function and dysfunction from Drosophila models.

Seoyoung Park, Nikita Kozhushko, Thomas H Wight

|Jul 07, 2025
Clu1/Clu form mitochondria-associated granules upon metabolic transitions and regulate mitochondrial protein translation via ribosome interactions.

Leonor Miller-Fleming, Wing Hei Au, Laura Raik

|Jun 21, 2024
Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models.

Wing Hei Au, Leonor Miller-Fleming, Alvaro Sanchez-Martinez

|Jan 25, 2024
Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models.

Aitor Martinez, Alvaro Sanchez-Martinez, Jake T Pickering

|Oct 27, 2023
N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity.

Sylvia Varland, Rui Duarte Silva, Ine Kjosås

|Aug 03, 2023
FBXO7/ntc and USP30 antagonistically set the ubiquitination threshold for basal mitophagy and provide a target for Pink1 phosphorylation in vivo.

Alvaro Sanchez-Martinez, Aitor Martinez, Alexander J Whitworth

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Frequent Collaborators

11 joint publications

Alvaro Sanchez-Martinez

3 joint publications

Guillaume M Hautbergue

3 joint publications

Aitor Martinez

3 joint publications

Juliette J Lee