James S Duncan

5PUBLICATIONS
17CO-AUTHORS
Solid tumoursMedical infection agents (incl. prions)Molecular targets
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Publications (5)

|Feb 23, 2026
MRCKα represses GEF-H1 mediated RhoA activation to promote ovarian cancer spheroid growth and invasion.

Aasiya Remtulla, Alison M Kurimchak, Alicia Canuel

|Mar 31, 2025
Characterization of MEK1/2 Degraders Uncovers a Kinase-Independent Role for MEK1/2 in the Stabilization and Maturation of CRAF.

Jason S Wasserman, Alison M Kurimchak, Carlos Herrera-Montávez

|Mar 22, 2023
FAM122A ensures cell cycle interphase progression and checkpoint control as a SLiM-dependent substrate-competitive inhibitor to the B55⍺/PP2A phosphatase.

Jason S Wasserman, Bulat Faezov, Kishan R Patel

|Aug 30, 2022
The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells.

Alison M Kurimchak, Carlos Herrera-Montávez, Sara Montserrat-Sangrà

|Feb 20, 2020
Functional proteomics interrogation of the kinome identifies MRCKA as a therapeutic target in high-grade serous ovarian carcinoma.

Alison M Kurimchak, Carlos Herrera-Montávez, Jennifer Brown

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