Shotaro Uehara

19PUBLICATIONS
6CO-AUTHORS
Haematological tumoursToxicology (incl. clinical toxicology)PharmacogenomicsMetabolic medicineMedical virology
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Publications (19)

|Nov 22, 2023
Chronic Toxoplasma infection affects gene expression of drug-metabolizing enzymes in mouse liver.

Yasuhiro Uno, Shotaro Uehara, Genki Ushirozako

|Nov 08, 2023
Empirical scaling factor for predicting human pharmacokinetic profiles of disproportionate metabolites using the Css-MRTpo method and chimeric mice with humanised livers.

Hidetaka Kamimura, Shotaro Uehara, Nao Yoneda

|Oct 06, 2023
Cytochrome P450 1A2 and 2C enzymes autoinduced by omeprazole in dog hepatocytes and human HepaRG and HepaSH cells are involved in omeprazole 5-hydroxylation and sulfoxidation.

Yasuhiro Uno, Shotaro Uehara, Genki Ushirozako

|Jan 09, 2023
The Unique Human N10-Glucuronidated Metabolite Formation from Olanzapine in Chimeric NOG-TKm30 Mice with Humanized Livers.

Shotaro Uehara, Yuichiro Higuchi, Nao Yoneda

|Oct 26, 2022
Newly identified tree shrew cytochrome P450 2B6 (CYP2B6) and pig CYP2B6b are functional drug-metabolising enzymes.

Yasuhiro Uno, Genki Ushirozako, Shotaro Uehara

|Sep 23, 2022
Selection of the candidate compound at an early stage of new drug development: retrospective pharmacokinetic and metabolic evaluations of valsartan using common marmosets.

Shogo Matsumoto, Shotaro Uehara, Hidetaka Kamimura

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