Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Derek P Claxton

9PUBLICATIONS
19CO-AUTHORS
Medical biochemistry - proteins and peptides (incl. medical proteomics)GlycoconjugatesStructure and dynamics of materialsCheminformatics and quantitative structure-activity relationshipsElectrical energy transmission, networks and systems
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (9)

Sort by Publication Date:
|Feb 08, 2024
Integrative analysis of pathogenic variants in glucose-6-phosphatase based on an AlphaFold2 model.

Matt Sinclair, Richard A Stein, Jonathan H Sheehan

|Mar 30, 2023
Molecular mechanisms of catalytic inhibition for active site mutations in glucose-6-phosphatase catalytic subunit 1 linked to glycogen storage disease.

Matt Sinclair, Richard A Stein, Jonathan H Sheehan

|Jan 06, 2021
Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na<sup>+</sup> in ion-coupled drug efflux.

Steven Castellano, Derek P Claxton, Emel Ficici

|Dec 03, 2020
Structure and assembly of CAV1 8S complexes revealed by single particle electron microscopy.

Bing Han, Jason C Porta, Jessica L Hanks

|Feb 21, 2020
Sequence and structural determinants of ligand-dependent alternating access of a MATE transporter.

Kevin L Jagessar, Derek P Claxton, Richard A Stein

|Jul 11, 2019
The N-terminal domain of an archaeal multidrug and toxin extrusion (MATE) transporter mediates proton coupling required for prokaryotic drug resistance.

Kevin L Jagessar, Hassane S Mchaourab, Derek P Claxton

Pageof 2

Frequent Collaborators

2 joint publications

Eric Gouaux

2 joint publications

Emad Tajkhorshid

2 joint publications

Richard A Stein

1 joint publications

Swastik Phulera

1 joint publications

Hongtao Zhu

1 joint publications

Nate Yoder

1 joint publications

Kevin L Jagessar

1 joint publications

Bing Han

1 joint publications

Richard M O'Brien

1 joint publications

Elad Binshtein

Frequent Collaborators

2 joint publications

Eric Gouaux

2 joint publications

Emad Tajkhorshid

2 joint publications

Richard A Stein

1 joint publications

Swastik Phulera

Top Related Videos

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on : Jan 16, 2019

11.0K
Spectrophotometric Methods for the Study of Eukaryotic Glycogen Metabolism
07:59

Spectrophotometric Methods for the Study of Eukaryotic Glycogen Metabolism

Published on : Aug 19, 2021

3.8K
Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane (SSM)-Based Electrophysiology
09:12

Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane (SSM)-Based Electrophysiology

Published on : May 03, 2021

2.8K
See more related videos

Top Related Videos

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on : Jan 16, 2019

11.0K
Spectrophotometric Methods for the Study of Eukaryotic Glycogen Metabolism
07:59

Spectrophotometric Methods for the Study of Eukaryotic Glycogen Metabolism

Published on : Aug 19, 2021

3.8K
Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane (SSM)-Based Electrophysiology
09:12

Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane (SSM)-Based Electrophysiology

Published on : May 03, 2021

2.8K
See more related videos