Michy P Kelly

7PUBLICATIONS
2CO-AUTHORS
Psychology of ageingProteins and peptidesEpigenetics (incl. genome methylation and epigenomics)Memory and attentionCentral nervous system
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (7)

|Jun 25, 2025
Age-Related Increases in PDE11A4 Protein Expression Trigger Liquid-Liquid Phase Separation (LLPS) of the Enzyme That Can Be Reversed by PDE11A4 Small Molecule Inhibitors.

Elvis Amurrio, Janvi H Patel, Marie Danaher

|Jun 06, 2025
Molecular mechanisms regulating PDE11A4 age-related liquid-liquid phase separation (LLPS) and its reversal by selective, potent and orally-available PDE11A4 small molecule inhibitors both in vitro and in vivo.

E Amurrio, J Patel, M Danaher

|Dec 22, 2023
The Sleep Quality- and Myopia-Linked PDE11A-Y727C Variant Impacts Neural Physiology by Reducing Catalytic Activity and Altering Subcellular Compartmentalization of the Enzyme.

Irina Sbornova, Emilie van der Sande, Snezana Milosavljevic

|Sep 08, 2022
Conserved age-related increases in hippocampal PDE11A4 cause unexpected proteinopathies and cognitive decline of social associative memories.

Katy Pilarzyk, Latarsha Porcher, William R Capell

|Sep 23, 2021
Aging triggers an upregulation of a multitude of cytokines in the male and especially the female rodent hippocampus but more discrete changes in other brain regions.

Latarsha Porcher, Sophie Bruckmeier, Steven D Burbano

|Jul 29, 2021
A genetic basis for friendship? Homophily for membrane-associated PDE11A-cAMP-CREB signaling in CA1 of hippocampus dictates mutual social preference in male and female mice.

Abigail J Smith, Reagan Farmer, Katy Pilarzyk

Pageof 2

Frequent Collaborators

1 joint publications

Gonzalo S Tejeda

1 joint publications

Katy Pilarzyk