Dimitrios-Ilias Balourdas

12PUBLICATIONS
53CO-AUTHORS
Molecular targetsData visualisation and computational (incl. parametric and generative) designEpigenetics (incl. genome methylation and epigenomics)Cheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and design
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Publications (12)

|Apr 28, 2026
DARPins as pan-reactivators of temperature-sensitive p53 cancer mutants.

|Feb 26, 2026
Targeting the p53 cancer mutants Y220C, Y220N, and Y220S with the small-molecule stabilizer rezatapopt.

Danai Mavridi, Julianne S Funk, Dimitrios-Ilias Balourdas

|Apr 17, 2025
Structure-Guided Design of ISOX-DUAL-Based Degraders Targeting BRD4 and CBP/EP300: A Case of Degrader Collapse.

Anthony K Edmonds, Dimitrios-Ilias Balourdas, Graham P Marsh

|Jan 09, 2025
DARPin-induced reactivation of p53 in HPV-positive cells.

Philipp Münick, Alexander Strubel, Dimitrios-Ilias Balourdas

|Jan 08, 2025
Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.

Julianne S Funk, Maria Klimovich, Daniel Drangenstein

|Jun 11, 2024
Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators.

Dimitrios-Ilias Balourdas, Anja M Markl, Andreas Krämer

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Frequent Collaborators

11 joint publications

Andreas C Joerger

5 joint publications

Stefan Knapp

4 joint publications

Thorsten Stiewe

4 joint publications

Julianne S Funk