Aman P Singh
6PUBLICATIONS
9CO-AUTHORS
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Publications (6)
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|Dec 19, 2024
Translational PK-PD model for in vivo CAR-T-cell therapy delivered using CAR mRNA-loaded polymeric nanoparticle vector.Se Jin Kim, Ganesh M Mugundu, Aman P Singh
|Nov 07, 2024
Quantitative pharmacology of dual-targeted bicistronic CAR-T-cell therapy using multiscale mechanistic modeling.Mei-Chi Su, Agnish Dey, Erfan Maddah
|Jul 14, 2023
Development of a multiscale mechanistic modeling framework integrating differential cellular kinetics of CAR T-cell subsets and immunophenotypes in cancer patients.Ahmed M Salem, Ganesh M Mugundu, Aman P Singh
|Oct 25, 2022
From Cold to Hot: Changing Perceptions and Future Opportunities for Quantitative Systems Pharmacology Modeling in Cancer Immunotherapy.Vincent Lemaire, David Bassen, Mike Reed
|Apr 11, 2020
Evolution of the Systems Pharmacokinetics-Pharmacodynamics Model for Antibody-Drug Conjugates to Characterize Tumor Heterogeneity and In Vivo Bystander Effect.Aman P Singh, Gail M Seigel, Leiming Guo
|Dec 20, 2019
Development of a quantitative relationship between CAR-affinity, antigen abundance, tumor cell depletion and CAR-T cell expansion using a multiscale systems PK-PD model.Aman P Singh, Xirong Zheng, Xiefan Lin-Schmidt
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