Brian T O'Neill

3PUBLICATIONS
3CO-AUTHORS
Biomolecular modelling and designBiomedical imagingCheminformatics and quantitative structure-activity relationships
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Publications (3)

|Apr 04, 2018
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation.

Brian T O'Neill, Elizabeth M Beck, Christopher R Butler

|Jan 23, 2018
Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain.

Lei Zhang, Laigao Chen, Jason K Dutra

|Nov 03, 2017
Spiropiperidine Sultam and Lactam Templates: Diastereoselective Overman Rearrangement and Metathesis followed by NH Arylation.

Luis A Martinez-Alsina, John C Murray, Leanne M Buzon

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Frequent Collaborators

2 joint publications

Lei Zhang

1 joint publications

Christopher R Butler

1 joint publications

Michael A Brodney