Tom Huxford

13PUBLICATIONS
30CO-AUTHORS
Cellular immunologyFunctional materialsAutoimmunityHaematological tumoursImmunogenetics (incl. genetic immunology)
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Publications (13)

|Jul 10, 2026
Cryo-EM reveals alternative modes of dimerization driving activation of IKK.

|Jul 11, 2025
Incorporating Metal-Ligand and Salt-Bridge Interactions in the Design of Protein Heterodimers.

Brian Maniaci, Matthew Mealka, Andrey A Bobkov

|Jun 30, 2025
Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate.

Prateeka Borar, Tapan Biswas, Ankur Chaudhuri

|Aug 26, 2024
HDX-MS Analysis of Catalytic Activation of IKK2 in the IκB Kinase Complex.

William Suryajaya, Tapan Biswas, Shandy Shahabi

|Jul 03, 2024
Structural and biochemical analyses of the nuclear IκBζ protein in complex with the NF-κB p50 homodimer.

Norman Zhu, W Eric Rogers, David K Heidary

|May 06, 2024
Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.

Matthew Mealka, Nicole A Sierra, Diego Avellaneda Matteo

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Frequent Collaborators

3 joint publications

Gourisankar Ghosh

2 joint publications

Amarnath Natarajan

2 joint publications

Christal D Sohl

2 joint publications

Smarajit Polley