Jinyi Xu

48PUBLICATIONS
37CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designMolecular targetsProteins and peptidesMedical devices
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Publications (48)

|Jul 20, 2026
From Structure to Selectivity: Integrating CADD and AIDD in Rational Medicinal Chemistry Strategies for DYRK1A Inhibitor Discovery.

|Mar 13, 2026
Discovery of Novel HPK1 Inhibitors via Chemistry-Based Direct-to-Bioassay Screening and SAR Optimization.

Yiping Duan, Chen He, Zhichao Guo

|Feb 10, 2026
Discovery of Novel Snail Inhibitors Derived from Omeprazole for Antiatherosclerotic Therapy: A Structure-Based Approach.

Zhaolan Zeng, Yang Lu, Mengsha Fang

|Jan 23, 2026
Discovery of SY-589, a Highly Potent and Orally Bioavailable Polθ Helicase Inhibitor for the Treatment of HR-Deficient Tumors.

Chongxun Ge, Dazhi Feng, Song Shi

|Dec 05, 2025
Discovery of Novel Bifunctional Agents as Potent TRK Inhibitors and Degraders against xDFG Mutation Resistance.

Jian Song, Jingjie Zhu, Wenjian Zhu

|Nov 18, 2025
Construction of Small-Molecule Deubiquitinase-Targeting Chimeras to Reactivate and Stabilize Mutant p53 Y220C in Vitro and in Vivo.

Chen He, Junda Li, Chenxi Cui

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Frequent Collaborators

18 joint publications

Shengtao Xu

14 joint publications

Hong Yao

5 joint publications

Zhe-Sheng Chen

4 joint publications

Hequan Yao