Jeremy Murray

9PUBLICATIONS
32CO-AUTHORS
Characterisation of biological macromoleculesCheminformatics and quantitative structure-activity relationshipsMolecular targetsBiologically active moleculesBiomolecular modelling and design
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Publications (9)

|Dec 02, 2025
Discovery of Potent, Selective and Efficacious Aminopyrazole Inhibitors of PLK4.

Joon Won Jeong, Trevor Chang, Jeremy M Murray

|Jun 18, 2025
Optimization of Brain Penetrant SARM1 Orthosteric Inhibitors and Discovery of Their Paradoxical Subinhibitory Activation.

Samantha A Green, Russell T Smith, Jessica M Grandner

|Jun 19, 2024
Optimization of a Novel DEL Hit That Binds in the Cbl-b SH2 Domain and Blocks Substrate Binding.

Jun Liang, Michael J Lambrecht, Teresita L Arenzana

|Sep 22, 2023
Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2).

Mingshuo Zeng, Jessica M Grandner, Marian C Bryan

|Oct 24, 2022
Overcoming Preclinical Safety Obstacles to Discover (<i>S</i>)-<i>N</i>-((1,2,3,5,6,7-Hexahydro-<i>s</i>-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5<i>H</i>-pyrazolo[5,1-<i>b</i>][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor.

Christopher McBride, Lynnie Trzoss, Davide Povero

|Aug 05, 2022
GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1.

Alexander M Taylor, Chris Bailey, Lisa D Belmont

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Frequent Collaborators

2 joint publications

Robin Larouche-Gauthier

2 joint publications

Jessica M Grandner

1 joint publications

Peter S Dragovich

1 joint publications

Jack D Sadowsky